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KMID : 0903519980410060477
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1998 Volume.41 No. 6 p.477 ~ p.482
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Development of LTD4 antagonists using QSAR
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Abstract
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In order to discover new Leukotriene D, antagonists, Quantitative Structure-Activity Relationships (QSAR) were applied based on the known data. A series of chalcone derivatives were selected for the training set. A candidate was predicted using QSAR and synthesized, and its biological activity was tested.
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